Main finding: Patients with Dry Eye Disease on n−3 fatty acids (omega-3 fatty acids) for 1 year did not have significantly better outcomes than placebo.
Purpose: To evaluate the effects of n−3 fatty acid supplementation on dry eye disease
Study type: Randomized controlled Trial
Condition: Dry Eye Disease
Participants: Moderate-to-severe dry eye disease
n=349
Intervention:
Group 1: fish-derived n−3 eicosapentaenoic and docosahexaenoic acids (3000mg daily)
Group 2: Placebo
The mean change in the OSDI score and clinical parameters (conjunctival and corneal staining score, TBUT, Schirmer’s test) was not significantly different between the active supplement group and the placebo group
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