Laser treatment in Age-related Macular Degeneration

In patient with intermediate AMD, subthreshold nanosecond laser (SNL) did not significantly slow progression rate to late AMD. A post hoc analysis however showed SNL may slow progression in patients without coexistent reticular pseudodrusen, and may be inappropriate in patients with the latter.(LEAD, 2019).{Guymer RH, Wu Z, Hodgson LAB, Caruso E, Brassington KH, Tindill N, Aung KZ, McGuinness MB, Fletcher EL, Chen FK, Chakravarthy U, Arnold JJ, Heriot WJ, Durkin SR, Lek JJ, Harper CA, Wickremasinghe SS, Sandhu SS, Baglin EK, Sharangan P, Braat S, Luu CD; Laser Intervention in Early Stages of Age-Related Macular Degeneration Study Group. Subthreshold Nanosecond Laser Intervention in Age-Related Macular Degeneration: The LEAD Randomized Controlled Clinical Trial. Ophthalmology. 2019 Jun;126(6):829-838.}