iStent
Last updated: April 3rd, 2022
Summary of Evidence
Efficacy
iStent + Phaco vs Phaco alone
There was a greater reduction in IOP without medication after iStent inject implantation with cataract surgery versus cataract surgery alone at 2 years, with excellent safety.{Samuelson TW, Sarkisian SR Jr, Lubeck DM, Stiles MC, Duh YJ, Romo EA, Giamporcaro JE, Hornbeak DM, Katz LJ; iStent inject Study Group. Prospective, Randomized, Controlled Pivotal Trial of an Ab Interno Implanted Trabecular Micro-Bypass in Primary Open-Angle Glaucoma and Cataract: Two-Year Results. Ophthalmology. 2019 Jun;126(6):811-821.}
Hydrus vs iStent
The Hydrus had a greater rate of complete surgical success and reduced medication use compared to 2 istent at 1 year.(COMPARE, 2020){Ahmed IIK, Fea A, Au L, Ang RE, Harasymowycz P, Jampel HD, Samuelson TW, Chang DF, Rhee DJ. A Prospective Randomized Trial Comparing Hydrus and iStent Microinvasive Glaucoma Surgery Implants for Standalone Treatment of Open-Angle Glaucoma: The COMPARE Study. Ophthalmology. 2020 Jan;127(1):52-61.}