Macular Hole
Last updated: February 9th, 2022
Summary of Evidence
Vitrectomy
Vitrectomy is effective in improving visual acuity, resulting in a moderate visual gain, and in achieving hole closure in people with idiopathic macular hole. {Parravano M, Giansanti F, Eandi CM, Yap YC, Rizzo S, Virgili G. Vitrectomy for idiopathic macular hole. Cochrane Database Syst Rev. 2015 May 12;2015(5):CD009080.}
Facedown positioning following large full-thickness macular hole surgery is more likely to achieve closure compared with facing forward, but do support the possibility that visual acuity outcomes may be superior.(PIMS, 2020). {Pasu S, Bell L, Zenasni Z, Lanz D, Simmonds IA, Thompson A, Yorston D, Laidlaw DAH, Bunce C, Hooper R, Bainbridge JWB; Positioning In Macular Hole Surgery (PIMS) Study Group. Facedown Positioning Following Surgery for Large Full-Thickness Macular Hole: A Multicenter Randomized Clinical Trial. JAMA Ophthalmol. 2020 Jul 1;138(7):725-730.}