Transepithelial corneal crosslinking for keratoconus.
Hersh PS, Lai MJ, Gelles JD, Lesniak SP.
J Cataract Refract Surg. 2018 Mar;44(3):313-322. Full text
| Metrics.
Main finding: Transepithelial corneal crosslinking resulted in significant improvement in maximum keratometry and uncorrected visual acuity at 1 year.
Purpose: To evaluate outcomes of transepithelial corneal crosslinking.
Study type: Prospective case series
Condition: Keratoconus
Participants: Age ≥ 14yo, CDVA < 20/20, diagnosis of keratoconus
n=82 eyes (56 patients)
Intervention:
-Riboflavin 0.1% and topical anesthetic containing benzalkonium chloride
-Ultraviolet-A exposure at 3mW/cm2 with Riboflavin administration either every 1 minute or every 2 minutes
At 1 year, maximum K decreased significantly by 0.45 diopters (D)
Mean UDVA significantly improved by 0.7 lines
CDVA improved by 0.2 lines.
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