Main finding: Intraocular lens implantation does not result in better vision or protection against postoperative glaucoma, and increases the risk of requiring early reoperation in children younger than 2 years with bilateral or unilateral cataract.
Study characteristics:
Name: IoLunder2 study
Purpose: To evaluate outcomes following intraocular lens implantation following cataract surgery in children aged 2
years and younger
Type: Observational cohort study
Condition: Congenital/infantile cataract
Year results published: 2018
Participants: ≤2 years old who underwent surgery for unilateral or bilateral congenital/infantile cataract
n=256 patients
Primary intraocular lens implantation was not associated with better visual outcome or reduced incidence of postoperative glaucoma than conventional treatment in children with bilateral or unilateral cataract
It was associated with a five times higher risk of reoperation for visual axis opacity requiring general anaesthesia in children with bilateral cataract and a 20 times higher risk in children with unilateral cataract.
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