Glaucoma Intensive Treatment Study (GITS): Initial intraocular pressure reduction by mono- versus multi-therapy

Participants: Newly diagnosed glaucoma

• n=295 eyes (240 patients)

Intervention:

Group 1: Immediate intensive treatment (multi‐therapy comprising three different IOP‐lowering substances as two medications and 360° selective or argon LTP 1 week later)
Group 2: conventional stepwise treatment starting with mono-therapy

The median IOP reduction was 11.0 in the intensive group and 6.3 in the conventional group at 1 month.

A larger proportion of the multi‐therapy patients reached each target IOP level