Contents

PEDIG: Weekend atropine for severe amblyopia

June 1, 2009

Clinical trial

Treatment of severe amblyopia with weekend atropine: results from 2 randomized clinical trials.

Repka MX, Kraker RT, Beck RW, Birch E, Cotter SA, Holmes JM, Hertle RW, Hoover DL, Klimek DL, Marsh-Tootle W, Scheiman MM, Suh DW, Weakley DR.

J AAPOS. 2009 Jun;13(3):258-63.
Full text | Metrics.

Main finding: Weekend atropine can improve visual acuity in children 3 to 12 years of age with severe amblyopia

 

  • Purpose: To determine the effectiveness of weekend atropine for severe amblyopia in children aged 3 to 12 years of age
  • Type: Randomized controlled Trial
  • Condition: Amblyopia

Participants: Children aged 3 to 12 years old with amblyopia (Strabismic, anisometropic, or both)
-VA in amblyopic eye 20/125-20/400
-VA in sound eye 20/25 or better

 

  • n=100 patients

 

Intervention:

 

Trial 1

 

Group 1: Weekend atropine + plano lens for sound eye
Group 2: Weekend atropine + full spectacle correction for sound eye

 

Trial 2

 

Group 1: Weekend atropine
Group 2: Patching (2 hours/day)

 

Outcome (18 weeks) Atropine + plano Atropine + correction
VA improvement (lines) +5.1 +4.5
Outcome (18 weeks) Atropine Patching
VA improvement (lines) +1.5 +1.8

Share This Article :

Updated on March 7th, 2022

Source Archive

© 2025 - sourceshed