A

• A 3-year Randomized Clinical Trial of MiSight Lenses for Myopia Control

• A Phase 3, Randomized, Double-Masked Study of OTX-101 Ophthalmic Solution 0.09% in the Treatment of Dry Eye Disease

• A Prospective Randomized Trial Comparing Hydrus and iStent Microinvasive Glaucoma Surgery Implants for Standalone Treatment of Open-Angle Glaucoma (COMPARE)

• A randomized placebo-controlled trial of idebenone in Leber's hereditary optic neuropathy

• A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa

• A randomized, double-masked, placebo-controlled, multicenter comparison of loteprednol etabonate ophthalmic suspension, 0.5%, and placebo for treatment of keratoconjunctivitis sicca in patients with delayed tear clearance

• A Study of the Efficacy and Safety of Ranibizumab Injection in Patients With Macular Edema Secondary to Branch Retinal Vein Occlusion (BRAVO)

• A Study of the Efficacy and Safety of Ranibizumab Injection in Patients With Macular Edema Secondary to Central Retinal Vein Occlusion (CRUISE)

• Accelerated Pulsed High-Fluence Corneal Cross-Linking for Progressive Keratoconus

• Adalimumab in combination with methotrexate for the treatment of juvenile idiopathic arthritis associated uveitis (SYCAMORE)

• Advanced Glaucoma Intervention Study (AGIS)

• Age-Related Eye Disease Study (AREDS) I

• Age-Related Eye Disease Study (AREDS) II

• Ahmed Baerveldt comparison (ABC) study

• Ahmed Versus Baerveldt (AVB) study

• ALTAIR

• Antibody for the Treatment of Predominantly Classic Choroidal Neovascularization (CNV) in Age-related Macular Degeneration (ANCHOR)

• Atropine for the Treatment of Myopia (ATOM) I

• Atropine for the Treatment of Myopia (ATOM) II

B

• Bevacizumab Eliminates the Angiogenic Threat for Retinopathy of Prematurity (BEAT-ROP)

• Branch Vein Occlusion Study (BVOS)

• Brolucizumab for Neovascular Age-Related Macular Degeneration (HAWK AND HARRIER)

C

• Central Vein Occlusion Study (CVOS)

• Clinical efficacy of intravitreal aflibercept versus panretinal photocoagulation for best corrected visual acuity in patients with proliferative diabetic retinopathy at 52 weeks (CLARITY)

• Collaborative Initial Glaucoma Treatment Study (CIGTS)

• Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study

• Collaborative Normal Tension Glaucoma Study (CNTGS)

• Collaborative Ocular Melanoma Study (COMS) – LARGE TUMOURS

• Collaborative Ocular Melanoma Study (COMS) – MEDIUM TUMOURS

• Collaborative Ocular Melanoma Study (COMS) – SMALL TUMOUR

• Comparison of Age-Related Macular Degeneration Treatments Trials (CATT)

• Congenital Esotropia Observational Study

• Corneal crosslinking and intracorneal ring segments for keratoconus: A randomized study of concurrent versus sequential surgery

• Cryotherapy for Retinopathy of Prematurity Study (CRYO-ROP)

D

• Dexamethasone intravitreal implant in patients with diabetic macular edema (MEAD)

• Diabetes Control and Complications Trial (DCCT)

• Diabetic Retinopathy Vitrectomy Study (DRVS)

• DRCR.net PROTOCOL AB: Vitrectomy vs Aflibercept for Vitreous Hemorrhage

• DRCR.net PROTOCOL B: Focal/grid photocoagulation vs intravitreal triamcinolone for diabetic macular edema

• DRCR.net PROTOCOL I: Ranibizumab With Prompt or Deferred Laser Versus Laser or Triamcinolone Plus Deferred Ranibizumab for Diabetic Macular Edema

• DRCR.net PROTOCOL S: Panretinal Photocoagulation vs Intravitreous Ranibizumab for Proliferative Diabetic Retinopathy

• DRCR.net PROTOCOL T: Aflibercept, Bevacizumab, or Ranibizumab for Diabetic Macular Edema

• DRCR.net PROTOCOL V: Initial Management With Aflibercept vs Laser Photocoagulation vs Observation on Vision Loss Among Patients With Diabetic Macular Edema

• DRCR.net PROTOCOL W: Intravitreous Anti-Vascular Endothelial Growth Factor vs Sham Treatment for Prevention of Vision-Threatening Complications of Diabetic Retinopathy

• Dry Eye Assessment and Management (DREAM) Study

E

• Early Manifest Glaucoma Trial (EMGT)

• Early Treatment for Retinopathy Of Prematurity (ETROP)

• Early vs. late infantile strabismus surgery study (ELISSS)

• Effect of Corneal Cross-linking versus Standard Care on Keratoconus Progression in Young Patients (KERALINK)

• Effect of Loteprednol Etabonate 0.5% on Initiation of Dry Eye Treatment With Topical Cyclosporine 0.05%

• Effectiveness of early lens extraction for the treatment of primary angle-closure glaucoma (EAGLE)

• Efficacy and safety of verteporfin photodynamic therapy in combination with ranibizumab or alone versus ranibizumab monotherapy in patients with symptomatic macular polypoidal choroidal vasculopathy (EVEREST)

• Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65-mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial

• Endophthalmitis Vitrectomy study

• Eplerenone for chronic central serous chorioretinopathy (VICI)

• European Glaucoma Prevention Study (EGPS)

• European Society of Cataract & Refractive Surgeons (ESCRS) multicenter study

• Extension trial of ranibizumab for choroidal neovascularization secondary to age-related macular degeneration (HORIZON)

F

• Femtosecond laser-assisted versus phacoemulsification cataract surgery (FEMCAT)

• Fluorouracil Filtering Surgery Study

G

• Giant-Cell Arteritis Actemra (GiACTA) trial

• Glaucoma Intensive Treatment Study (GITS): Initial intraocular pressure reduction by mono- versus multi-therapy

• Glaucoma Intensive Treatment Study (GITS): Selective laser trabeculoplasty versus topical medication as initial glaucoma treatment

H

• Half-Dose Photodynamic Therapy versus High-Density Subthreshold Micropulse Laser Treatment in Chronic Central Serous Chorioretinopathy (PLACE AND REPLACE)

• Herpetic Eye Disease Study (HEDS) I

• Herpetic Eye Disease Study (HEDS) II

• Hydrus Microstent for Lowering IOP in Glaucoma Patients Undergoing Cataract Surgery (HORIZON)

• Hyperosmolar Eye Drops for Diurnal Corneal Edema in Fuchs’ Endothelial Dystrophy

I

• IDIOPATHIC INTRACRANIAL HYPERTENSION TREATMENT TRIAL

• Implantable Device for Lowering Intraocular Pressure in Glaucoma Patients Undergoing Cataract Surgery (COMPASS)

• Improvement in inner retinal function in glaucoma with nicotinamide (vitamin B3) supplementation: A crossover randomized clinical trial

• Infant Aphakia Treatment Study (IATS)

• Intravitreal Aflibercept for Diabetic Macular Edema (VISTA AND VIVID)

• Intravitreal Aflibercept for Polypoidal Choroidal Vasculopathy (PLANET)

• Intravitreal Aflibercept for the Improvement of Moderately Severe to Severe Nonproliferative Diabetic Retinopathy (PANORAMA)

• Intravitreal aflibercept injection for macular edema due to central retinal vein occlusion (COPERNICUS)

• Intravitreal Aflibercept Injection for Macular Edema Resulting from Central Retinal Vein Occlusion (GALILEO)

• Intravitreal Aflibercept Injection in Patients with Myopic Choroidal Neovascularization (MYRROR)

• Intravitreal Bevacizumab vs. Triamcinolone for Patients with Diabetic Macular Edema at the Time of Cataract Surgery (DIMECAT)

• IOLunder2 study (IOLUNDER2)

L

• Laser in Glaucoma and ocular HyperTension (LiGHT)

• Laser Intervention in Early Stages of Age-Related Macular Degeneration (LEAD)

• Latanoprostene Bunod 0.024% and Timolol Maleate 0.5% in Open-Angle Glaucoma or Ocular Hypertension (LUNAR)

• Latanoprostene Bunod 0.024% versus Timolol Maleate 0.5% in Subjects with Open-Angle Glaucoma or Ocular Hypertension (APOLLO)

• Lifitegrast for the Treatment of Dry Eye Disease (OPUS)

• Long-Term Outcomes after Surgery for Late In-The-Bag Intraocular Lens Dislocation: A Randomized Clinical Trial

• Low-Concentration Atropine for Myopia Progression (LAMP)

• Low-Pressure Glaucoma Treatment Study (LGTS)

• Lucentis, Eylea, Avastin in Vein Occlusion (LEAVO)

M

• Macular Photocoagulation Study (MPS)

• Minimally Classic/Occult Trial of the Anti-VEGF Antibody Ranibizumab in the Treatment of Neovascular Age-Related Macular Degeneration (MARINA)

• MiSight Assessment Study Spain (MASS). A 2-year randomized clinical trial

• Mycotic Ulcer Treatment Trial (MUTT)

N

• Netarsudil/Latanoprost Fixed-Dose Combination for Elevated Intraocular Pressure (MERCURY)

• Non-arteritic anterior ischemic optic neuropathy: role of systemic corticosteroid therapy

O

• Ocular Hypertension Treatment Study (OHTS)

• Optic Neuritis Treatment Trial (ONTT)

• Outcomes of corneal neurotisation using processed nerve allografts: a multicentre case series

P

• PEDIG: Anisometropic amblyopia

• PEDIG: Associations between age and baseline factors and surgical outcomes

• PEDIG: Atropine vs patching in moderate amblyopia aged < 7 years old

• PEDIG: Atropine vs patching in moderate amblyopia aged 7-12 years old

• PEDIG: Bilateral LRC vs unilateral RCRS for Intermittent XT

• PEDIG: Binocular Ipad game in children aged 13-16 years

• PEDIG: Binocular Ipad game in children aged 7-12 years

• PEDIG: Immediate vs delayed glasses for moderate hyperopia in 1-2 year olds

• PEDIG: Immediate vs delayed glasses for moderate hyperopia in 3-5 year olds

• PEDIG: Observation for intemittent XT

• PEDIG: Weekend atropine for severe amblyopia

• Phase 3, Randomized, 20-Month Study of Bimatoprost Implant in Open-Angle Glaucoma and Ocular Hypertension (ARTEMIS 1)

• PIER: ranibizumab for neovascular age-related macular degeneration

• Pneumatic Retinopexy vs Vitrectomy for the Management of Primary Rhegmatogenous Retinal Detachment Outcomes Randomized Trial (PIVOT)

• Positioning In Macular hole Surgery (PIMS)

• PREMED I: prevention of cystoid macular edema after cataract surgery in nondiabetics

• PREMED II: prevention of cystoid macular edema after cataract surgery in diabetics

• Primary Tube vs. Trabeculectomy Study (PTVT)

• Prospective Randomized Trial Comparing Efficacy of Topical Loteprednol Etabonate 0.5% Versus Cyclosporine-A 0.05% for Treatment of Dry Eye Syndrome Following Hematopoietic Stem Cell Transplantation

R

• Randomized Clinical Trial Comparing Femtosecond LASIK and Small-Incision Lenticule Extraction

• Ranibizumab for the treatment of choroidal neovascularisation secondary to pathological myopia (REPAIR)

• Ranibizumab in patients with choroidal neovascularization secondary to pathologic myopia (RADIANCE)

• Ranibizumab monotherapy or combined with laser versus laser monotherapy for diabetic macular edema (RESTORE)

• Ranibizumab Therapy for Diabetic Macular Edema (RISE AND RIDE)

• Rho Kinase Elevated IOP Treatment (ROCKET) trials

• Riboflavin/ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus

S

• Scleral buckling versus primary vitrectomy in rhegmatogenous retinal detachment (SPR Study)

• SCORE2: Bevacizumab vs Aflibercept on Visual Acuity Among Patients With Macular Edema Due to Central Retinal Vein Occlusion

• Standalone Ab Interno Gelatin Microstent Implantation versus Standalone Trabeculectomy (XEN VS TRAB)

• Standard Care vs. COrticosteroid for REtinal Vein Occlusion (SCORE) - BRVO

• Standard Care vs. COrticosteroid for REtinal Vein Occlusion (SCORE) - CRVO

• Steroids after Laser Trabeculoplasty (SALT)

• Steroids for Corneal Ulcers Trial (SCUT)

• Supplemental Therapeutic Oxygen for Prethreshold Retinopathy of Prematurity (STOP-ROP)

T

• Teprotumumab for the Treatment of Active Thyroid Eye Disease (OPTIC)

• Thymectomy in Myasthenia Gravis (MGTX)

• Toddler Aphakia and Pseudophakia Study (TAPS)

• Tolerating Subretinal Fluid in Neovascular Age-Related Macular Degeneration Treated with Ranibizumab Using a Treat-and-Extend Regimen (FLUID)

• Transepithelial corneal collagen crosslinking for progressive keratoconus: 24-month clinical results

• Transepithelial corneal crosslinking for keratoconus

• Treat-and-Extend versus Monthly Regimen in Neovascular Age-Related Macular Degeneration (TREND)

• Treatment of age-related macular degeneration with photodynamic therapy (TAP)

• Treatment of neurotrophic keratopathy with minimally invasive corneal neurotisation: long-term clinical outcomes and evidence of corneal reinnervation

• Tube Versus Trabeculectomy (TVT) Study

• Two different treatment regimens of ranibizumab 0.5 mg for neovascular age-related macular degeneration with or without polypoidal choroidal vasculopathy in Chinese patients (DRAGON)

• Two multicenter, randomized studies of the efficacy and safety of cyclosporine ophthalmic emulsion in moderate to severe dry eye disease. CsA Phase 3 Study Group

U

• UK Glaucoma Treatment Study (UKGTS)

• UK Prospective Diabetes Study (UKPDS)

• United States Multicenter Clinical Trial of Corneal Collagen Crosslinking for Keratoconus Treatment

V

• Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Wet Age-Related Macular Degeneration (VIEW)

• VEGF Trap-Eye in Patients with Diabetic Macular Edema (DA VINCI)

• Verteporfin In Photodynamic Therapy (VIP)

• Verteporfin versus ranibizumab for polypoidal choroidal vasculopathy (LAPTOP)

• VISUAL I: Adalimumab in Patients with Active Noninfectious Uveitis

• VISUAL II: Adalimumab in Patients with Active Noninfectious Uveitis

• VISUAL III: Adalimumab in Patients with Active Noninfectious Uveitis

Z

• Zhongshan Angle Closure Prevention (ZAP) trial