Early vitrectomy for severe vitreous hemorrhage in diabetic retinopathy. Two-year results of a randomized trial. Diabetic Retinopathy Vitrectomy Study report 2.
Arch Ophthalmol. 1985 Nov;103(11):1644-52. Full text
Main finding: In patients with Type 1 Diabetes, there was a clear advantage of early vitrectomy for vitreous haemorrhage. No such advantage was found in Type 2 Diabetes.
Type: Randomized controlled Trial
Condition: Vitreous haemorrhage in Diabetes retinopathy
Participants: Type 1/2 Diabetes, Severe vitreous haemorrhage, VA 5/200 to LP
Definition of Vitreous Haemorrhage: obscures macula and retina within 15 degrees from centre of macula
n=616
Intervention:
Group 1: Early vitrectomy
Group 2: Late vitrectomy (Deferred for 1 year)
In patients with Type 1 Diabetes, there was a clear advantage of early vitrectomy for vitreous haemorrhage.
Outcomes
Groups
Early Vitrectomy
Late Vitrectomy
VA 10/20 or better
Total
25%
15%
Type 1 DM
36%*
12%*
Type 2 DM
16%
16%
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