Main finding: Tube shunt surgery had a higher success rate compared to trabeculectomy with MMC
Purpose: To report 3-year results of the Tube Versus Trabeculectomy Study.
Study type: Randomized controlled trial
Condition: Uncontrolled glaucoma
Participants: 18 to 85yo, previous trabeculectomy, cataract extraction with intraocular lens implantation or both, uncontrolled glaucoma with intraocular pressure 18-40
n=212
Intervention:
Group 1: Baerveldt glaucoma implant (350-mm(2))
Group 2: Trabeculectomy + MMC (MMC 0.4 mg/ml for 4 minutes)
The cumulative probability of failure was 15.1% in the tube group and 30.7% in the trabeculectomy group
Both procedures had similar IOP reduction and use of supplemental medical therapy
Postoperative complications were higher in the trabeculectomy group (60%) than in the tube group (39%)
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