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Laser in Glaucoma and ocular HyperTension (LiGHT)

April 13, 2019

Clinical trial

Selective laser trabeculoplasty versus eye drops for first-line treatment of ocular hypertension and glaucoma (LiGHT): a multicentre randomised controlled trial.

Gazzard G, Konstantakopoulou E, Garway-Heath D, Garg A, Vickerstaff V, Hunter R, Ambler G, Bunce C, Wormald R, Nathwani N, Barton K, Rubin G, Buszewicz M.

Lancet. 2019 Apr 13;393(10180):1505-1516.
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Main finding: Selective laser trabeculoplasty is an effective first-line treatment for open angle glaucoma and ocular hypertension

 

  • Purpose: To compare Selective laser trabeculoplasty vs eyedrops as first-line treatment in open angle glaucoma or ocular hypertension.
  • Study type: Randomized controlled trial
  • Condition: Open angle glaucoma, Ocular Hypertension

Participants: ≥18yo with newly diagnosed, untreated OAG or ocular hypertension

 

  • n=718

 

Intervention:

 

  • Group 1: SLT
  • Group 2: Eyedrops

At 3 years, 74·2% of patients in the SLT group required no drops to maintain intraocular pressure at target

 

76·6% of these required only one treatment

 

There was no difference in health-related QOL between groups

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Updated on March 7th, 2022

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