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Toddler Aphakia and Pseudophakia Study (TAPS)


Main finding: Intraocular lens implantation between 7-24 months of age had a low incidence of complications, reoperations and glaucoma at 4 years.

 

Study characteristics:

 

  • Name: Toddler Aphakia and Pseudophakia Study (TAPS)
  • Purpose: To evaluate outcomes of unilateral cataract surgery in children between 7 to 24 months of age
  • Type: Retrospective case series
  • Condition: Congenital cataract
  • Year results published: 2019

Participants: Unilateral or bilateral cataract surgery between 7 months to 24 months of age as part of the Infant Aphakia Treatment Study

 

  • n=56
Outcomes TAPS cohort
Mean age of cataract surgery 13.9 months
Intraoperative complications 7%
VA ≥20/40 at 5 years 11%
VA ≤20/200 at 5 years 44%
Adverse events 24%
Additional unplanned intraocular surgery 14%


Main finding: Intraocular lens placement resulted in similar visual acuity outcomes with aphakia management at 5 years, though with an increased risk of visual axis opacification. Adverse events were associated with younger age at surgery and microcornea.

 

Study characteristics:

 

  • Name: Toddler Aphakia and Pseudophakia Study (TAPS)
  • Purpose: To evaluate outcomes of bilateral cataract surgery in children aged 1 to 7 months of age
  • Type: Retrospective case series
  • Condition: Congenital cataracts
  • Year results published: 2020

Participants: Bilateral cataract surgery with at least one eye undergoing surgery between 1 to 7 months of age.

 

  • n=178 eyes (96 patients)
Outcomes TAPS cohort
Visual acuity at 5 years Median VA 20/45
Corrected VA <20/40 29% of better seeing eyes, 15% of worse seeing eyes
Corrected VA ≥20/200 1% in better seeing eyes, 12% in worse seeing eyes
Adverse events Risk factors for Glaucoma/glaucoma suspect Younger age at surgery Smaller corneal diameter (<9.5mm)
Visual axis opacification 32% in pseudophakic eyes, 8% in aphakic eyes

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Updated on March 7th, 2022

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