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Paul tube

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Last updated: August 5th, 2022

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Summary of Evidence

The PAUL® glaucoma implant (PGI) was able to achieve sustained IOP reduction with reduction of medications at 2 years postsurgery in patients with advanced glaucoma.{Tan MCJ, Choy HYC, Koh Teck Chang V, Aquino MC, Sng CCA, Lim DKA, Loon SC, Chew Tec Kuan P. Two-Year Outcomes of the Paul Glaucoma Implant for Treatment of Glaucoma. J Glaucoma. 2022 Jun 1;31(6):449-455. doi: 10.1097/IJG.0000000000001998. Epub 2022 Feb 18. PMID: 35180153; PMCID: PMC9148669.}

Evidence

1. Outcomes

Retrospective review

2022 Tan et.al.

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2022
Retrospective review

The PGI was able to achieve sustained IOP reduction with reduction of medications at 2 years postsurgery in patients with advanced glaucoma.{Tan MCJ, Choy HYC, Koh Teck Chang V, Aquino MC, Sng CCA, Lim DKA, Loon SC, Chew Tec Kuan P. Two-Year Outcomes of the Paul Glaucoma Implant for Treatment of Glaucoma. J Glaucoma. 2022 Jun 1;31(6):449-455. doi: 10.1097/IJG.0000000000001998. Epub 2022 Feb 18. PMID: 35180153; PMCID: PMC9148669.}

Tan et.al.
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Cohort study

2021 Vallabh et.al.

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2021
Cohort study

This study presents results of a novel glaucoma drainage device-the PAUL® glaucoma implant (PGI) which significantly reduces IOP and number of medications with minimal complications.{Vallabh NA, Mason F, Yu JTS, Yau K, Fenerty CH, Mercieca K, Spencer AF, Au L. Surgical technique, perioperative management and early outcome data of the PAUL® glaucoma drainage device. Eye (Lond). 2021 Sep 20:1–6. doi: 10.1038/s41433-021-01737-1. Epub ahead of print. PMID: 34545206; PMCID: PMC8450714.}

Vallabh et.al.
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Clinical trial

2020 Koh et.al.

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2020
Clinical trial

The PGI demonstrated comparable efficacy with other currently available implants, with almost three quarters of the enrolled patients with refractory glaucoma achieving complete surgical success after 1 year of follow-up.{Koh V, Chew P, Triolo G, Lim KS, Barton K; PAUL Glaucoma Implant Study Group. Treatment Outcomes Using the PAUL Glaucoma Implant to Control Intraocular Pressure in Eyes with Refractory Glaucoma. Ophthalmol Glaucoma. 2020 Sep-Oct;3(5):350-359. doi: 10.1016/j.ogla.2020.05.001. Epub 2020 May 11. PMID: 32980037.}

Koh et.al.
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References

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