Latanoprost bunod
Last updated: February 8th, 2022
Summary of Evidence
Latanoprost bunod vs Timolol
At all 9 time points (IOP was measured at 8 am, 12 pm, and 4 pm of each follow-up visit ), the mean IOP in the study eye was significantly lower in the LBN 0.024% group than in the timolol 0.5% group.(APOLLO, 2016) {Weinreb RN, Scassellati Sforzolini B, Vittitow J, Liebmann J. Latanoprostene Bunod 0.024% versus Timolol Maleate 0.5% in Subjects with Open-Angle Glaucoma or Ocular Hypertension: The APOLLO Study. Ophthalmology. 2016 May;123(5):965-73.}
Mean IOP reduction in the LBN group was significantly greater than timolol at all but the first time point in this study (week 2, 8 AM).(LUNAR, 2016) {Medeiros FA, Martin KR, Peace J, Scassellati Sforzolini B, Vittitow JL, Weinreb RN. Comparison of Latanoprostene Bunod 0.024% and Timolol Maleate 0.5% in Open-Angle Glaucoma or Ocular Hypertension: The LUNAR Study. Am J Ophthalmol. 2016 Aug;168:250-259.}