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Primary Tube vs. Trabeculectomy Study (PTVT)

Treatment Outcomes in the Primary Tube Versus Trabeculectomy Study after 3 Years of Follow-up.

Gedde SJ, Feuer WJ, Lim KS, Barton K, Goyal S, Ahmed IIK, Brandt JD.

Ophthalmology. 2020 Mar;127(3):333-345.
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Main finding: There was no significant difference in the rate of surgical failure between tube shunt surgery and trabeculectomy at 3 years

Purpose: To report 3-year results of the Primary Tube Versus Trabeculectomy Study.
Study type: Randomized controlled trial
Condition: Uncontrolled glaucoma

Participants: 18-85yo medically uncontrolled glaucoma, IOP 18-40, no previous incisional ocular surgery

Intervention:

The cumulative probability of failure was 33% in the tube group and 28% in the trabeculectomy group (P = 0.17)

Trabeculectomy/MMC achieved lower IOP with fewer glaucoma medications

Mean IOP was 14.0 mmHg in the tube group and 12.1mmHg in the trabeculectomy group

The number of glaucoma medications was 2.1 in the tube group and 1.2 in the trabeculectomy group

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Updated on March 7th, 2022