Primary Angle closure and Primary Angle closure Glaucoma
Last updated: March 5th, 2022
Summary of Evidence
Primary Angle Closure (PAC)
Prophylatic Laser peripheral iridotomy
The incidence of Angle closure disease was very low in patients who were primary angle closure suspects. Prophylactic laser PI for PACS is not recommended.(ZAP, 2019) {He M, Jiang Y, Huang S, Chang DS, Munoz B, Aung T, Foster PJ, Friedman DS. Laser peripheral iridotomy for the prevention of angle closure: a single-centre, randomised controlled trial. Lancet. 2019 Apr 20;393(10181):1609-1618.}
Primary Angle Closure and PACG
Clear lens extraction vs Laser peripheral iridotomy
Clear-lens extraction showed greater efficacy and was more cost-effective than laser peripheral iridotomy, and should be considered as an option for first-line treatment.(EAGLE, 2016) {Azuara-Blanco A, Burr J, Ramsay C, Cooper D, Foster PJ, Friedman DS, Scotland G, Javanbakht M, Cochrane C, Norrie J; EAGLE study group. Effectiveness of early lens extraction for the treatment of primary angle-closure glaucoma (EAGLE): a randomised controlled trial. Lancet. 2016 Oct 1;388(10052):1389-1397}