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PEDIG: Immediate vs delayed glasses for moderate hyperopia in 3-5 year olds

December 1, 2019

Clinical trial

A Randomized Clinical Trial of Immediate Versus Delayed Glasses for Moderate Hyperopia in Children 3 to 5 Years of Age.

Holmes JM, Kulp MT, Dean TW, Suh DW, Kraker RT, Wallace DK, Petersen DB, Cotter SA, Crouch ER, Lorenzana IJ, Ticho BH, Verderber LC, Weise KK.

Am J Ophthalmol. 2019 Dec;208:145-159.
Full text | Metrics.

Main finding: The study had insufficient enrollment and retention and therefore was unable to determine whether immediate glasses prescription reduces failure rate. Low failure rates (reduced VA or binocularity) however suggest that immediate glasses prescription may not be needed.

 

  • Purpose: To compare glasses prescription vs observation for managing moderate hyperopia.
  • Type: Randomized controlled Trial
  • Condition: Hyperopia

Participants: Children aged 3 to 5 years old
-moderate hyperopia (+3.0 to +6.0 in at least one eye)

 

n=130 patients

 

Intervention:

 

Group 1: Glasses
Group 2: Observation (glasses prescribed if reduced VA, reduced stereoacuity or manifest strabismus)

Failure criteriae:
-distance VA or stereoacuity below age norms
-manifest strabismus observed
-strabismus surgery performed.

 

71% of children completed the primary outcome follow up examination. Failure occurred in 12% of the glasses group vs 9% of the observation group.

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Updated on March 7th, 2022

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