Main finding: Macular grid photocoagulation is not recommended for macular oedema secondary to CRVO
Purpose: To evaluate the efficacy of macular grid photocoagulation in preserving or improving central visual acuity in eyes with macular edema due to central vein occlusion
Study type: Randomized controlled trial.
Condition: Central retinal vein occlusion
Participants: Central retinal vein occlusion with macular oedema, VA ≤ 20/50
n=155
Intervention:
Group 1:Macular grid photocoagulation
Group 2: Control
There was no difference in visual acuity between treated and untreated eyes at any point during the follow-up period.
October 1, 1995
Clinical trial
A randomized clinical trial of early panretinal photocoagulation for ischemic central vein occlusion. The Central Vein Occlusion Study Group N report.
Main finding: Prophylactic PRP does not totally prevent iris/angle neovascularisation (CVOS definition). The study authors recommend careful close observation initially and prompt PRP of eyes in which iris/angle neovascularisation develops.
Purpose: To answer whether prophylactic panretinal photocoagulation in ischemic central vein occlusion prevents development of 2 clock hours of iris neovascularization or any angle neovascularization (TC-INV/ANV) or whether it is more appropriate to apply PRP only when TC-INV/ANV occurs.
Study type: Randomized controlled trial.
Condition: Central retinal vein occlusion
Participants: Ischaemic Central retinal vein occlusion
n=181
Intervention:
Group 1: Immediate Prophylactic PRP
Group 2: Close observation
2 clock hours of iris neovascularization or any angle neovascularization (TC-INV/ANV) developed less often in prophylactically treated than untreated eyes, but the difference was not statistically significant.
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